Give differences : Mendelian disorders and Chromosomal disorders
Mendelian disorders | Chromosomal disorders |
$(1)$ These are due to alteration in a single gene. | $(1)$ These are caused due to absence or excess of one or more chromosomes of abnormal arrangement of one/more chromosomes. |
$(2)$ They are transmitted into generations through Mendelian principles of inheritance. | $(2)$ They are transmitted as the affected individual is sterile. |
$(3)$They may be recessive or dominant in nature. | $(3)$ This is always dominant in nature. |
$(4)$ Examples : Colour blindness, Phenylketonuria. | $(4)$ Examples : Down's syndrome, Turner's syndrome. |
The cause of Turner's syndrome in man is
In which genetic condition, each cell in the affected person, has three sex chromosomes $XXY$ ?
The person with klinefelter's syndrome
A disease caused by an autosomal primary non disjunction is